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Distinct Parkinson s Disease Symptoms Tied to Different Brain Pathways

Distinct Parkinsonâs Disease Symptoms Tied to Different Brain Pathways Identification of neural circuits clarifies motor vs. cognitive symptoms, aiding efforts to improve treatments Lim Lab, UC San Diego A three-dimensional rendering of a mouse hemisphere shows brain-wide projection patterns of GPe neurons labeled by mRuby2 (soma, axonal fibers) and eGFP (pre-synaptic sites). Newswise Parkinson’s disease (PD) is well known as a debilitating disease that gradually worsens over time. Although the disease’s progression has been largely tied to the loss of motor functions, non-motor symptoms, including the loss of cognitive abilities, often emerge early in the disease. Much less understood is the role that specific neural circuits play in these distinct motor and non-motor functions.

Horia pribiagChristopher dabin yoonEric hou jen wangKwanghun chungAmanda ngoc tranJun hyeok choiXiao yun wangVaroth lilascharoenStefan carl pateAnandamahidol foundation fellowshipUniversity of california san diegoNational institutes of healthCalifornia san diegoNature neuroscienceNeurobiology sectionBiological sciences

An interactive visual database for American Sign Language reveals how signs are organized in the mind

“Desire” and “still” don’t rhyme in English, but they do rhyme in American Sign Language. Just as poets can evoke emotions and meaning by choosing words that echo one another in English, actress and Tony nominee Lauren Ridloff chooses signs that visually echo one another in her ASL adaptation of Anne Michaels’ poem “Not.” For spoken languages, there are many resources that contain information about how often words are used, which words rhyme and other information not found in a dictionary. But until recently, there was no such thing for sign languages. We are four researchers who study psycholinguistics, linguistics, neuroscience and deaf education. Our team of deaf and hearing scientists worked with a group of software engineers to create the ASL-LEX database that anyone can use for free. We cataloged information on nearly 3,000 signs and built a visual, searchable and interactive database that allows scientists and linguists to work with ASL in entirely new ways.

United statesLauren ridloffAnne michaelAmerican signZed sevcikova sehyrCavan imagesAmerican sign languageSign languageData baseஒன்றுபட்டது மாநிலங்களில்அன்னே மைக்கேல்அமெரிக்கன் அடையாளம்கேவன் படங்கள்அமெரிக்கன் அடையாளம் மொழிஅடையாளம் மொழிதகவல்கள் அடித்தளம்

Cleaning dummies with chemicals may increase risk of food allergies, study warns

Cleaning dummies with chemicals may increase risk of food allergies, study warns
9news.com.au - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from 9news.com.au Daily Mail and Mail on Sunday newspapers.

Anne louise ponsonbyMental healthFlorey institute of neuro scienceFlorey instituteBarwon infant studyமன ஆரோக்கியம்மிதவை நிறுவனம் ஆஃப் நரம்பியல் அறிவியல்மிதவை நிறுவனம்பார்வோன் குழந்தை படிப்பு

Ashok Soota launches SKAN Medical research trust for Ageing and Neurological disorders, Commits Rs 200 Cr investment

(1) BENGALURU, India, April 5, 2021 /PRNewswire/ Ashok Soota today announced the creation of SKAN, probably India s first not-for-profit entity in the private sector, exclusively for medical research. The research for the projects will be done through reputed partners, and directly in-house. The strategic partner for Neurological research is the Centre for Brain Research (CBR) at Indian Institute Science, Bangalore (IISc). CBR is putting together a consortium to handle the first project on Parkinson s disease. The strategic partner for Ageing is the upcoming St. John s Geriatric Centre (SJGC), to be located on the St John s Hospital campus. Soota has agreed to fund the setting up of the Centre for Research in Ageing and Geriatrics (CRAG) at the SJGC and to support joint projects. In Ageing, the approach will be to go wide into relatively under-researched areas and will include the establishment of a large community-based research cohort. For Neurological research, the plan will b

Kostenloser wertpapierhandelAshok sootaPrnewswire ashok sootaIndian institute scienceCentre for researchJohn geriatric centreCentre for brain researchBrain researchGeriatric centreHappiest mindsMedi calஇந்தியன் நிறுவனம் அறிவியல்மையம் க்கு ஆராய்ச்சிஜான் வயதான மையம்மையம் க்கு மூளை ஆராய்ச்சிமூளை ஆராய்ச்சி

New blueprint of brain connections reveals extensive reach of central regulator

E-Mail IMAGE: Shown here in green are branches, or axons, from cells in the substantia nigra region that connect to the midbrain. Red spots label where cells connect. view more Credit: Lauren McElvain / Kleinfeld lab / UC San Diego) Thousands of our daily activities, from making coffee to taking a walk to saying hello to a neighbor, are made possible through an ancient collection of brain structures tucked away near the center of the cranium. The cluster of neurons known as the basal ganglia is a central hub for regulating a vast array of routine motor and behavior functions. But when signaling in the basal ganglia is weakened or broken, debilitating movement and psychiatric disorders can emerge, including Parkinson s disease, Tourette s syndrome, attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder.

United statesYuncong chenJohnj ngaiBrenda bloodgoodLauren mcelvainG stefano brigidiNeurophysics laboratory of professor david kleinfeldNational institutes of healthZuckerman institute principal investigator rui costaBrain researchDivision of biological sciences section neurobiologyColumbia vagelos college of physiciansUniversity of utah school medicineUniversity of california san diegoTourette association of americaDivision of physical sciences department physics